1.Iinxalenye ezisisiseko ze-tablet press
I-Punch kwaye ufe: I-Punch kunye nokufa zizinto ezisisiseko ze-tablet press, kwaye isibini ngasinye se-punch siqulunqwe ngamacandelo amathathu: i-punch ephezulu, i-middle die kunye ne-punch ephantsi.Ukwakhiwa kweepuntshi eziphezulu kunye nezantsi zifana, kwaye ububanzi beepuntshi nazo ziyafana.Amanqindi amanqindi aphezulu nasezantsi ahambelana nemingxunya yokufa ye-die middle die, kwaye angatyibilika phezulu kwaye ehle ngokukhululekileyo phakathi komngxuma wokufa, kodwa akuyi kubakho zithuba apho umgubo unokuvuza..Ubungakanani bokucwangcisa i-die bubukhulu obuqhelekileyo obudibeneyo, obunokutshintshwa.Iimpawu zediyezi zimelwe yi-diameter ye-punch okanye i-diameter ye-diameter ephakathi, ngokubanzi i-5.5-12mm, nganye i-0.5mm yinkcazo, kwaye kukho ukucaciswa kwe-14 iyonke.
I-punch kunye ne-die iphantsi koxinzelelo olukhulu ngexesha lenkqubo ye-tablet, kwaye kaninzi yenziwe ngentsimbi yokuthwala (njenge-crl5, njl.) kunye nokushisa kuphathwe ukuphucula ubunzima babo.
Kukho iintlobo ezininzi zeepunch, kwaye ukumila kwepunch kuchongwa ngumfanekiso ofunwayo wethebhulethi.Ngokwemilo yesakhiwo sokufa, inokwahlulwa ibe yizangqa kunye neemilo ezikhethekileyo (kubandakanywa iipolygons kunye neegophe);iimilo zamacandelo e-punch zisicaba, i-hypotenuse, i-concave engekho nzulu, i-concave enzulu kwaye ibanzi.Iingqindi ezimcaba kunye ne-hypotenuse zisetyenziselwa ukucinezela iipilisi ezisicaba ze-cylindrical, ii-punches ze-concave ezinzulu zisetyenziselwa ukucinezela iipilisi ze-biconvex, i-concave punch enzulu isetyenziselwa ukucinezela iipilisi ze-tablet ezigqunyiweyo, kwaye iipuntshi ezidibeneyo zisetyenziselwa ukucinezela iipilisi ze-biconvex.Iiflakes ezimile.Ukuze kube lula ukuchongwa kunye nokuthathwa kwamayeza, amanqaku afana negama leyeza, idosi kunye nemigca ethe nkqo kunye nethe tyaba nayo inokukrolwa ekupheleni kobuso bokufa.Ukucinezela iipilisi zeedosi ezahlukeneyo, ukufa kunye nobukhulu obufanelekileyo kufuneka kukhethwe.
2.Inkqubo yokusebenza ye-tablet press
Inkqubo yokusebenza yoshicilelo lwethebhulethi inokwahlulwa ibe ngamanyathelo alandelayo:
①Inxalenye yepunch yepunch esezantsi (indawo yayo yokusebenza iphezulu) idlulela kumngxuma wokufa ophakathi ukusuka kwisiphelo esisezantsi sombindi wokufa ukutywina emazantsi ombindi wokufa;
②Sebenzisa i-adder ukugcwalisa umngxuma wokufa osembindini ngeyeza;
③ Inxalenye yenqindi yenqindi ephezulu (indawo yayo yokusebenza isezantsi) iwela kumngxuma wokufa ophakathi ukusuka kwisiphelo esiphezulu somngxunya wokufa ophakathi, kwaye yehla kwi-stroke ethile ukucofa umgubo ube ngamacwecwe;
④I-punch ephezulu iphakamisa iphuma emngxunyeni, kwaye i-punch esezantsi iphakamisa ukutyhala ithebhulethi iphume kumngxunya ophakathi wokufa ukugqiba inkqubo yetafile;
⑤Nxinzelela phantsi kwindawo yokuqala kwaye ulungiselele ukuzaliswa okulandelayo.
3.Umgaqo womatshini wokubethela
① Ukulawula umthamo.Iipilisi ezahlukeneyo zineemfuno zedosi ezahlukeneyo.Ulungelelwaniso lwedosi enkulu luphunyezwa ngokukhetha iipuntshi ezinobubanzi bepunch ezahlukeneyo, ezifana neepuntshi ezinobubanzi obuyi-6mm, 8mm, 11.5mm, kunye ne-12mm.Emva kokuba ubungakanani bokufa bukhethiwe, ulungelelwaniso lwedosi encinci kukulungelelanisa ubunzulu bepunch esezantsi eyongeza kumngxunya ophakathi wokufa, ngaloo ndlela itshintsha ubude bokwenyani bomngxuma wokufa ophakathi emva kokutywinwa ngasemva, kunye nokulungelelanisa umthamo wokuzaliswa kwechiza kwi. umngxuma wokufa.Ngoko ke, kufuneka kubekho indlela yokulungelelanisa indawo yokuqala ye-punch ephantsi kumngxuma wokufa kwi-tablet press ukuhlangabezana neemfuno zohlengahlengiso lwedosi.Ngenxa yomahluko kumthamo othile phakathi kweebhetshi ezahlukeneyo zamalungiselelo omgubo, lo msebenzi wohlengahlengiso uyimfuneko kakhulu.
Kulawulo lwethamo, umthetho-siseko wesenzo somxheshi ukwanempembelelo enkulu.Ngokomzekelo, ichiza le-granular lixhomekeke kubunzima balo kwaye liqengqeleka ngokukhululekileyo kumngxuma wokufa ophakathi, kwaye imeko yalo yokuzaliswa ikhululekile.Ukuba iindlela ezininzi zokungena ngenkani zisetyenziswa, amachiza amaninzi aya kuzaliswa kwimingxuma yokufa, kwaye imeko yokuzaliswa iya kuba nzima.
② Ukulawulwa kobunzima bethebhulethi kunye nesidanga sokuqina.Idosi yeyeza inqunywe ngokwemigqaliselo kunye ne-pharmacopoeia kwaye ayinakuguqulwa.Ngomda wexesha lokugcinwa, ukugcinwa kunye nokuchithwa, uxinzelelo lwedosi ethile luyafuneka ngexesha le-tablet, eliya kuchaphazela ubuninzi bokwenene kunye nokubonakala kwethebhulethi.Ukulawulwa koxinzelelo ngexesha lethebhulethi kubalulekile.Oku kuphunyezwa ngokulungelelanisa umlinganiselo osezantsi wepunch kumngxuma wokufa.Abanye oomatshini bokushicilela bethebhulethi abanayo kuphela intshukumo ephezulu nasezantsi yeepuntshi eziphezulu kunye nezantsi ngexesha lenkqubo yethebhulethi, kodwa banentshukumo ephezulu nasezantsi yeepuntshi ezisezantsi,
kunye nentshukumo ehambelanayo yeepuntshi eziphezulu kunye nezantsi zigqibezela inkqubo yethebhulethi.Nangona kunjalo, ukulawulwa koxinzelelo kuninzi kuqondwa yindlela yokulungelelanisa ukuhamba okunyukayo kunye nokuhla ukuqaphela ukulawulwa koxinzelelo kunye nokulawula.
Ixesha lokuposa: May-25-2022